What is the significance of the appearance of immunoglobulin M (IgM) in the workup of coccidioidomycosis?

Updated: Aug 27, 2019
  • Author: Duane R Hospenthal, MD, PhD, FACP, FIDSA, FASTMH; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

IgM has only qualitative significance, as the magnitude does not correlate with dissemination or extent of disease. Also, a high rate of false-positives is noted, especially in conditions that stimulate humoral immunity.


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