Which general lab studies are included in the workup of coccidioidomycosis?

Updated: Aug 27, 2019
  • Author: Duane R Hospenthal, MD, PhD, FACP, FIDSA, FASTMH; Chief Editor: Michael Stuart Bronze, MD  more...
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Because most patients recover spontaneously, pursuing documentation of coccidioidal infection is not imperative unless the patient is immunocompromised or has signs of severe progressive disease or dissemination. Diagnosis requires isolation of the organism in culture, identification on histologic specimens, or serologic testing.

The diagnostic evaluation is guided by the patient's clinical presentation and the clinician’s index of suspicion. General laboratory tests include a complete blood count (CBC) and erythrocyte sedimentation rate (ESR). Typical results are a normal white blood cell count or mild lymphocytosis, monocytosis, and/or eosinophilia (>5%) and an elevated ESR.

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