What is the pathophysiology of nonrespiratory transmission of coccidioidomycosis?

Updated: Aug 27, 2019
  • Author: Duane R Hospenthal, MD, PhD, FACP, FIDSA, FASTMH; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

In rare occurrences, direct inoculation of Coccidioides (eg, from contaminated penetrating objects).causes primary cutaneous coccidioidomycosis with lymphatic extension to the regional lymph nodes; these cases resolve without treatment. In 2009, a report alleged transmission of coccidioidomycosis to a human by a cat bite. [11] This occurred in a veterinary assistant who had been bitten on the hand by a cat that was later diagnosed with disseminated disease.

Case reports have documented rare instances of coccidioidomycosis transmitted through other modes. These include transplantation of organs from infected donors and sexually transmitted cases.


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