What is disseminated coccidioidomycosis?

Updated: Aug 27, 2019
  • Author: Duane R Hospenthal, MD, PhD, FACP, FIDSA, FASTMH; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Disseminated disease may occur in an otherwise healthy individual, but the risk is significantly higher in individuals with altered cellular immunity due to disease (eg, HIV infection, lymphoma), medical treatment (eg, corticosteroid therapy), or pregnancy. In addition, risk of dissemination or progressive pulmonary disease is higher in certain racial groups (eg, Filipinos, blacks). (See Epidemiology and Clinical Presentation.)

Extrapulmonary primary infections can occur with trauma causing a puncture wound from a contaminated object. Laboratory workers and children are especially at risk for cutaneous or soft tissue lesions, including chancres, with regional lymphadenitis. [6, 2, 3, 7, 4, 8, 9]


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