What is the role of coagulation studies in the management of severe dengue (dengue hemorrhagic fever)?

Updated: May 03, 2019
  • Author: Darvin Scott Smith, MD, MSc, DTM&H; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Coagulation studies may help to guide therapy in patients with severe hemorrhagic manifestations. Findings are as follows:

  • Prothrombin time is prolonged

  • Activated partial thromboplastin time is prolonged

  • Low fibrinogen and elevated fibrin degradation product levels are signs of disseminated intravascular coagulation


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