What are the Pan American Health Organization (PAHO) diagnostic criteria for dengue?

Updated: May 03, 2019
  • Author: Darvin Scott Smith, MD, MSc, DTM&H; Chief Editor: Michael Stuart Bronze, MD  more...
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Dengue fever presents in a nonspecific manner and may not be distinguishable from other viral or bacterial illness. According to the Pan American Health Organization (PAHO), the clinical description of dengue fever is an acute febrile illness of 2-7 days duration associated with 2 or more of the following:

  • Severe and generalized headache
  • Retro-orbital pain
  • Severe myalgias, especially of the lower back, arms, and legs
  • Arthralgias, usually of the knees and shoulders
  • Characteristic rash
  • Hemorrhagic manifestations
  • Leukopenia

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