What is the mortality rate of dengue in the US?

Updated: May 03, 2019
  • Author: Darvin Scott Smith, MD, MSc, DTM&H; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

As suggested by a reported case of a woman aged 63 years who died from complications of dengue acquired in New Mexico or Texas in 2012, the disease may not be adequately recognized in the United States as a source of potentially fatal acute febrile illness. The patient had initially been diagnosed with West Nile virus, but a postmortem bone marrow biopsy revealed the presence of dengue virus. [13, 14]

In addition, the patient’s records revealed that she met the clinical case definition for hemophagocytic lymphohistiocytosis, a hyperinflammatory syndrome that is sometimes associated with dengue and that, in this instance, was the cause of death.


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