Which medications in the drug class Anticholinergic Agents are used in the treatment of Dizziness, Vertigo, and Imbalance?

Updated: Mar 13, 2017
  • Author: Hesham M Samy, MD, PhD; Chief Editor: Robert A Egan, MD  more...
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Answer

Anticholinergic Agents

Anticholinergic agents are thought to work centrally by suppressing conduction in the vestibular-cerebellar pathways.

Glycopyrrolate (Robinul, Cuvposa)

Glycopyrrolate blocks the action of acetylcholine at parasympathetic sites.

Scopolamine (Transderm Scop)

Scopolamine blocks the action of acetylcholine at parasympathetic sites in smooth muscle, secretory glands, and the CNS. It antagonizes the actions of histamine and serotonin. Transdermal application may be the most effective for motion sickness. Use of scopolamine in the treatment of vestibular neuronitis is limited by the drug's slow onset of action. Severe adverse effects preclude its use in elderly. Glycopyrrolate is more effective and has fewer adverse effects, especially in elderly patients.


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