How is multiple sclerosis diagnosed?

Updated: Mar 13, 2017
  • Author: Hesham M Samy, MD, PhD; Chief Editor: Robert A Egan, MD  more...
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The diagnosis of multiple sclerosis requires the presence of dissemination in time and space (ie, different neurologic symptoms at different times). A careful history, a thorough examination, and serial follow-up combined with magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) analysis help establish the diagnosis; the diagnosis should not be based on MRI abnormalities alone. Disease-modifying therapy is available, but it is only modestly effective. The search for improved treatment is ongoing.

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