How is autoimmune inner-ear disease differentiated from Ménière disease?

Updated: Mar 13, 2017
  • Author: Hesham M Samy, MD, PhD; Chief Editor: Robert A Egan, MD  more...
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Answer

Patients with autoimmune inner-ear disease typically present with rapidly progressive, bilateral hearing loss, with or without vertigo. Initial onset may be unilateral. However, the rapid progression, bilateral involvement, and response to steroids distinguish this disorder from Ménière disease. Autoimmune inner-ear disease can occur with or without other autoimmune disease or laboratory evidence of a systemic inflammatory disorder. Specific laboratory markers for inner-ear antigenicity have low sensitivity and thus are of little clinical utility.


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