What are the CDC guidelines for treatment of chlamydial genitourinary infections (chlamydia) during pregnancy?

Updated: Sep 25, 2018
  • Author: Shahab Qureshi, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Pregnancy treatment considerations

Guidelines from the CDC recommend azithromycin 1 g orally as a single dose. Alternatives include amoxicillin 500 mg orally three times a day for 7 days as the preferred drug regimens for treating chlamydial infections in pregnancy, [54, 55] with erythromycin as another alternative. [40, 56, 57] Doxycycline, ofloxacin, and levofloxacin are contraindicated in pregnancy. Clindamycin is only partially effective in eradicating C trachomatis in men with nongonococcal urethritis, but it appears to be as efficacious as erythromycin in pregnant and nonpregnant women with C trachomatis infection. [58, 59, 60] Test-of-cure to document chlamydial eradication (preferably via NAAT) 3-4 weeks after therapy completion is recommended.


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