What is the role of PCR testing in the workup of chlamydial genitourinary infections (chlamydia)?

Updated: Sep 25, 2018
  • Author: Shahab Qureshi, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

The US Food and Drug Administration (FDA) recently cleared the Cepheid GeneXpert CT/NG (Xpert) rapid polymerase chain reaction (PCR) test as a moderate-complexity test. CT/NG GeneXpert is a real-time PCR assay that can be run on demand in less than 2 hours and has a test performance that is similar to that of existing nucleic acid amplification tests (NAATs) in both low- and high-prevalence populations. [39]

The C trachomatis nonculture tests have been largely replaced because of the superior performance of NAATs, even when performed on noninvasive specimens.


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