Which specimens should be obtained and assayed in the workup of Chlamydia trachomatis (C trachomatis) infection?

Updated: Sep 25, 2018
  • Author: Shahab Qureshi, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
  • Print
Answer

Endocervical, urethral, rectal, or oropharyngeal specimens should be obtained and assayed for C trachomatis infection in both males and females based on the patient’s sexual practices obtained by history. [31] A voided urine sample, whether midstream or first-void, effectively captures the chlamydial organism for nucleic acid amplification testing (NAAT). [32] NAATs are the most sensitive tests for these specimens and are therefore recommended for detecting C trachomatis infection. [33, 34] Self-collected vaginal swab specimens are equivalent in sensitivity and specificity to those collected by a clinician using NAATs. [35, 36, 33]


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!