What is the role of lab testing in the workup of chancroid?

Updated: Aug 05, 2019
  • Author: Joseph Adrian L Buensalido, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Answer

No laboratory testing is able to immediately confirm the diagnosis of chancroid. [3]

A definitive diagnosis of chancroid is based on isolation of H ducreyi on special media, but such tests are not readily available in many centers. In addition, lesion culture is inaccurate owing to the fastidious nature of the organism, with a sensitivity of less than 80%. [44, 45]

The nucleic acid amplification test (NAAT) is a multiplex PCR assay that yields a high detection rate, [46] although, no molecular assays have been cleared by the Food and Drug Administration (FDA) for use in the United States. [22]

The role of polymerase chain reaction (PCR) in rapid detection of H ducreyi is promising and may supersede culture in diagnosis. [44, 47]


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