Which medications in the drug class Antifungal Agents are used in the treatment of Cellulitis?

Updated: Jun 14, 2019
  • Author: Thomas E Herchline, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Antifungal Agents

Antifungal agents such as itraconazole and terbinafine work by inhibiting the biosynthesis of ergosterol, which is an essential component of the fungal cell membrane.

Itraconazole (Sporanox)

Itraconazole is a synthetic triazole that has fungistatic activity. It slows fungal cell growth by inhibiting cytochrome P-450–dependent synthesis of ergosterol, a vital component of fungal cell membranes.

Terbinafine (Lamisil, Terbinex)

Terbinafine inhibits squalene epoxidase, which decreases ergosterol synthesis, causing fungal cell death. Use medication until symptoms significantly improve.


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