Which medications in the drug class Fluoroquinolones are used in the treatment of Cellulitis?

Updated: Jun 14, 2019
  • Author: Thomas E Herchline, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Fluoroquinolones

Fluoroquinolones have broad-spectrum activity against gram-positive and gram-negative aerobic organisms. They inhibit DNA synthesis and growth by inhibiting DNA gyrase and topoisomerase, which is required for replication, transcription, and translation of genetic material.

Levofloxacin (Levaquin)

Levofloxacin is used to treat pseudomonal infections and infections due to multidrug-resistant gram-negative organisms.

Ciprofloxacin (Cipro)

Ciprofloxacin inhibits bacterial DNA synthesis and, consequently, growth by inhibiting DNA gyrase and topoisomerases, which are required for replication, transcription, and translation of genetic material.

Delafloxacin (Baxdela)

Delafloxacin inhibits bacterial DNA synthesis and growth by inhibiting bacterial topoisomerase IV and DNA gyrase. Delafloxacin exhibits concentration-dependent bactericidal activity against gram-positive and gram-negative bacteria in vitro.


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