Which antibiotics are recommended in the treatment of clostridial necrotizing infections?

Updated: Jun 14, 2019
  • Author: Thomas E Herchline, MD; Chief Editor: Michael Stuart Bronze, MD  more...
  • Print

For clostridial infections, first-line agents are clindamycin 600-900 mg/kg IV every 8 hours, as well as penicillin 2-4 MU IV every 4-6 hours.

Readers are encouraged to check the IDSA guidelines Website for the 2014 updated recommendations for the diagnosis and management of skin and soft-tissue infections.

See also the Medscape Reference articles Necrotizing fasciitis and Clostridial Gas Gangrene.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!