Which antibiotics are recommended in the treatment of clostridial necrotizing infections?

Updated: Jun 14, 2019
  • Author: Thomas E Herchline, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

For clostridial infections, first-line agents are clindamycin 600-900 mg/kg IV every 8 hours, as well as penicillin 2-4 MU IV every 4-6 hours.

Readers are encouraged to check the IDSA guidelines Website for the 2014 updated recommendations for the diagnosis and management of skin and soft-tissue infections.

See also the Medscape Reference articles Necrotizing fasciitis and Clostridial Gas Gangrene.


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