Which antibiotics are recommended in the treatment of severe streptococcal necrotizing infections in adults?

Updated: Jun 14, 2019
  • Author: Thomas E Herchline, MD; Chief Editor: Michael Stuart Bronze, MD  more...
  • Print
Answer

First-line agents in managing severe adult streptococcal infection are penicillin 2-4 MU IV every 4-6 hours plus  clindamycin 600-900 mg/kg IV every 8 hours. [2] For patients with severe penicillin hypersensitivity, use vancomycin, linezolid, quinupristin-dalfopristin, or daptomycin. Add an appropriate agent if a staphylococcal infection is present or suspected.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!