What are the common causes of monomicrobial necrotizing fasciitis?

Updated: Jun 14, 2019
  • Author: Thomas E Herchline, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Common causes of monomicrobial necrotizing fasciitis include Streptococcus pyogenes, Vibrio vulnificus, and Aeromonas hydrophila. [2] Polymicrobial necrotizing fasciitis is more common, especially in postoperative patients or in those with comorbid conditions, such as peripheral vascular disease, diabetes, and decubitus ulcers.

Clostridium species such as C perfringens, C septicum, C histolyticum, and C novyi are toxic causes of life-threatening gas gangrene, usually as a result of significant penetrating trauma or crush injuries that interrupt the blood supply. [2] Other predisposing factors include intracutaneous injection of black tar heroin (C perfringens, C novyi) or spontaneous gas gangrene (C septicum) in individuals with colonic lesions, adenocarcinoma, or neutropenia. [2]

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