How is erysipelas treated?

Updated: Jun 14, 2019
  • Author: Thomas E Herchline, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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As noted, streptococcal species are the most common causes of erysipelas and diffuse cellulitis or cellulitis that is not associated with a defined portal, and Staphylococcus aureus is the usual causative organism in cellulitis that is associated with furuncles, carbuncles, or abscesses. [2]

First-line treatment of erysipelas is either IV or PO penicillin, depending on the severity of the condition. In cases of cellulitis (except in areas with streptococcal/staphylococcal resistance), select a penicillinase-resistant semisynthetic penicillin or a first-generation cephalosporin. Clindamycin or vancomycin is an alternative in patients who are allergic to penicillin. [2]

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