How effective are antibiotics in the treatment of MRSA cellulitis?

Updated: Jun 14, 2019
  • Author: Thomas E Herchline, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Unfortunately, for patients with cellulitis surrounding abscess formation, 50% of MRSA strains also have inducible or constitutive clindamycin resistance. [2] Of the strains of S pyogenes resistant to macrolides, 99.5% seem to remain susceptible to clindamycin and 100% to penicillin. [2] Most community-acquired MRSA infections (CA-MRSA) are apparently susceptible to trimethoprim-sulfamethoxazole and tetracycline.

In 2011, the IDSA published updated guidelines regarding management of MRSA in adults and children, and in 2012, the updated IDSA guidelines for the Diagnosis and Treatment of Diabetic Foot Infections were published. [67, 68] Readers are encouraged to check the IDSA guidelines Web site for the 2014 updated recommendations for the diagnosis and management of skin and soft-tissue infections. [2]


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