What is the efficacy for antibiotics in the treatment of cat scratch disease (CSD)?

Updated: Feb 16, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Currently, only limited and/or anecdotal evidence supports the use of antibiotics in the treatment of typical CSD in immunocompetent hosts. Bartonella henselae is susceptible to many antibiotics in vitro. However, the susceptibility patterns do not predict efficacy in vivo. Bartonella is an intracellular bacterium and responds poorly to penicillin derivatives in vivo despite susceptibility in vitro.


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