Which histopathologic findings are characteristic of lymph nodes in cat scratch disease (CSD)?

Updated: Feb 16, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Histopathologic findings of the lymph nodes depend on the stage of infection. Lymphoid hyperplasia with arteriolar proliferation, reticulum cell hyperplasia, and widening of arteriolar walls are seen early in the disease. Progression of the disease is manifested by granulomas. The centers of these granulomas are acellular and necrotic with surrounding histiocytes and lymphocytes. Microabscesses may develop as the granulomas and areas of necrosis coalesce.


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