What is the role of CT scanning in the diagnosis of cat scratch disease (CSD)?

Updated: Feb 16, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Michael Stuart Bronze, MD  more...
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In patients with disseminated CSD and persistent high fever, abdominal pain, and severe systemic symptoms, abdominal CT scanning may be helpful. Multiple lesions of the liver and spleen are the major manifestations seen on such scans.

These lesions are usually round or oval, ranging from 3-30 mm, and hypodense on noncontrast CT scans. [58] Injection of contrast material may yield hypodense, isodense, or marginally enhanced lesions when compared with normal parenchyma. Hepatosplenic lesions have been observed to spontaneously resolve or calcify over weeks to months.

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