What is the role of skin testing in the diagnosis of cat scratch disease (CSD)?

Updated: Feb 16, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

The CSD skin test is no longer recommended. The test is less sensitive and specific than serologic testing, poorly standardized, and not approved by the US Food and Drug Administration (FDA). [4] In addition, the test considered by some to be unsafe, as it uses a preparation derived from pus aspirated from suppurative lymph nodes of patients with CSD, and there is concern over the potential transmission of hepatitis viruses, HIV, and prions.


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