What is the efficacy of Enzyme-linked immunoassay (ELISA) testing for the diagnosis of catscratch disease (CSD)?

Updated: Feb 16, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

ELISA testing for IgM has a sensitivity of 95% and a specificity of 77%. ELISA for IgG has a sensitivity of only 18%. Genotypic and phenotypic differences between B henselae strains are widely encountered and lead to antigenic variation and difficulty in interpreting the results of serologic tests.


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