What are the uncommon dermatologic manifestations of cat scratch disease (CSD)?

Updated: Feb 16, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Michael Stuart Bronze, MD  more...
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Other dermatologic manifestations occur in approximately 5% of patients and are more likely to occur in patients with more severe or atypical disease. These manifestations include macular, maculopapular, morbilliform, and petechial rashes. They typically are nonpruritic and resolve in days to weeks. Cases of erythema multiforme, erythema nodosum, erythema annulare, and ecchymoses associated with thrombocytopenia have been reported in patients with CSD, but these are rare.

Characterized by painful, tender, subcutaneous nodules on the skin, erythema nodosum may present 1-6 weeks after onset of adenopathy in less than 1% of patients with CSD. These nodules resolve without sequelae.

Thrombocytopenia purpura is quite rare and is usually transient.

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