What are the central nervous system (CNS) symptoms of cat scratch disease (CSD)?

Updated: Feb 16, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

CNS findings are present in 5% of patients with CSD. In addition to headaches, these may include mental status changes, seizures, myelitis, transient peripheral neuropathy, and retinitis. The presence of abdominal pain with a history consistent with CSD suggests CSD hepatitis/splenitis, a self-limited granulomatous condition.

Table 1. Clinical Manifestations of CSD [4] (Open Table in a new window)

Sign or Symptom

Percentage, %

Average Duration, d

Adenopathy

100

14-180

Adenopathy only

52

14-180

Inoculation site

59-93

7

Fever >101°F (38.3°C)

32-60

6

Malaise/fatigue

29

13

Headache

13

4

Anorexia, weight loss, emesis

14

5

Splenomegaly

12

11

Sore throat

5

2

Rash

5

8.5

Parotid swelling

2

-

Conjunctivitis

4.5

-


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