Which medications in the drug class Antineoplastics, Monoclonal Antibody are used in the treatment of Cutaneous T-Cell Lymphoma?

Updated: Aug 15, 2018
  • Author: Lauren C Pinter-Brown, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Antineoplastics, Monoclonal Antibody

Monoclonal antibodies against a T-cell antigen may inhibit cell growth and proliferation of malignant cells.

Alemtuzumab (Campath, Lemtrada)

Alemtuzumab is a monoclonal antibody against CD52, an antigen found on B cells, T cells, and almost all CLL cells. It binds to the CD52 receptor of lymphocytes, slowing the proliferation of leukocytes.

Mogamulizumab (mogamulizumab-kpkc, Poteligeo)

CC chemokine receptor type 4 (CCR4)-directed monoclonal antibody indicated for adults with relapsed or refractory mycosis fungoides or Sézary syndrome after at least 1 prior systemic therapy.


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