Which medications in the drug class Topical Skin Products are used in the treatment of Cutaneous T-Cell Lymphoma?

Updated: Aug 15, 2018
  • Author: Lauren C Pinter-Brown, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Topical Skin Products

Agents that induce secretion of interferon and other cytokines have shown efficacy. The topical alkylating agent, mechlorethamine, has also been shown to be effective.

Imiquimod 5% cream (Aldara, Zyclara)

This agent binds to Toll-like receptors 7 and 8 and induces the secretion of interferon alfa and other cytokines. Its mechanism of action is unknown.

Mechlorethamine topical (Valchlor)

Mechlorethamine topical is an alkylating agent that inhibits rapidly proliferating cells. It is indicated for mycosis fungoides-type cutaneous T-cell lymphoma.

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