What is the drug treatment for cutaneous T-cell lymphoma (CTCL)?

Updated: Aug 15, 2018
  • Author: Lauren C Pinter-Brown, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Cutaneous T-cell lymphomas are a heterogeneous group of entities. One should distinguish indolent, low-risk mycosis fungoides and Sézary syndrome from aggressive HTLV-1–associated adult T-cell leukemia/lymphoma. [129]

Treatment for early stage cutaneous T-cell lymphomas includes topical therapies with or without interferon alfa or oral agents, while advanced-stage patients are treated with chemotherapy and novel agents. Multiagent cytotoxic regimens may be palliative, but they seem to lack a demonstrated survival benefit. [6]

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