What skin-targeted therapies are used in the treatment of cutaneous T-cell lymphoma (CTCL)?

Updated: Aug 15, 2018
  • Author: Lauren C Pinter-Brown, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

When mycosis fungoides is confined to the skin (cutaneous T-cell lymphoma [CTCL]), skin-targeted therapies, such as the following, are often effective in controlling manifestations [106] :

  • Topical corticosteroids

  • Heliotherapy

  • Photochemotherapy - Eg, psoralen plus UV-A (PUVA)

  • Topical application of nitrogen mustard (mechlorethamine) or carmustine (BCNU)

  • Radiotherapy - Including total skin electron beam irradiation


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