What is the role of extracorporeal photopheresis in the treatment of cutaneous T-cell lymphoma (CTCL)?

Updated: Aug 15, 2018
  • Author: Lauren C Pinter-Brown, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Extracorporeal photopheresis, either alone or in combination with other treatment modalities (eg, interferon alfa), is an effective treatment for Sézary syndrome and for erythrodermic mycosis fungoides, with overall response rates of 30-80% and complete response rates of 14-25%. [18] The alleged superiority of extracorporeal photopheresis over the traditional low-dose chemotherapy regimens has not been proven.


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