What are the histologic findings of subcutaneous panniculitis-like T-cell lymphoma?

Updated: Aug 15, 2018
  • Author: Lauren C Pinter-Brown, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

In subcutaneous panniculitis-like T-cell lymphoma, subcutaneous infiltrates simulate a panniculitis and show small, medium, or sometimes large pleomorphic T cells with hyperchromatic nuclei and often many macrophages. [31] The overlying epidermis and dermis are typically not involved. [91] Rimming of individual fat cells by neoplastic T cells is a helpful, although not completely specific, diagnostic feature. [29] Necrosis, karyorrhexis, and cytophagocytosis are common.


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