What are the histologic findings of adult T-cell leukemia/lymphoma in cutaneous T-cell lymphoma (CTCL)?

Updated: Aug 15, 2018
  • Author: Lauren C Pinter-Brown, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

In adult T-cell leukemia/lymphoma, the cutaneous nodules show a superficial or more diffuse infiltration of medium to large T cells with pleomorphic or multilobated nuclei, often with marked epidermotropism. The histologic picture may be the same as that seen with mycosis fungoides. In the smoldering type of adult T-cell leukemia/lymphoma, dermal infiltrates may be sparse, with only slightly atypical cells.


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