What are the physical findings of nasal-type extranodal NK/T-cell lymphoma?

Updated: Apr 20, 2020
  • Author: Lauren C Pinter-Brown, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Nasal-type extranodal NK/T-cell lymphoma usually appears as a destructive midfacial tumor or as multiple plaques or tumors, often with ulceration, preferentially on the trunk and extremities. Systemic symptoms such as fever, malaise, and weight loss may be present, and some cases are accompanied by a hemophagocytic syndrome.

Nasal-type extranodal NK/T-cell lymphoma has a variant that clinically resembles hydroa vacciniforme in which children, mainly in Latin America and Asia, have a papulovesicular eruption that typically occurs on sun-exposed areas, such as the face and upper extremities. [75, 76]

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