What are the physical findings of subcutaneous panniculitis-like T-cell lymphoma?

Updated: Apr 20, 2020
  • Author: Lauren C Pinter-Brown, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Subcutaneous panniculitis-like T-cell lymphoma is a rare form of cutaneous T-cell lymphoma. Patients are usually first seen with solitary or multiple nodules and plaques; these mainly involve the legs, although they may be more generalized. Ulceration is uncommon, but systemic symptoms such as fever, fatigue, and weight loss may be present. A hemophagocytic syndrome may be present and is generally associated with a rapidly progressive course. [71] Dissemination to extracutaneous sites is unusual. Subcutaneous panniculitis-like T-cell lymphoma may be preceded for years or decades by a seemingly benign panniculitis suggestive of chronic erythema nodosum. Rarely, it may produce scalp alopecia. [72]

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