What are the physical findings of acute adult T-cell leukemia/lymphoma?

Updated: Apr 20, 2020
  • Author: Lauren C Pinter-Brown, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Acute adult T-cell leukemia/lymphoma is characterized by the presence of leukemia, lymphadenopathy, organomegaly, hypercalcemia, and, in approximately 50% of cases, skin lesions. Skin lesions most commonly include nodules or tumors (33%), generalized papules (22%), or plaques (19%). [46] Chronic and smoldering variants frequently manifest as skin lesions that closely resemble mycosis fungoides, whereas circulating neoplastic T cells are few or absent.

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