What is the clinical history of syringotropic mycosis fungoides cutaneous T-cell lymphoma (CTCL)?

Updated: Aug 15, 2018
  • Author: Lauren C Pinter-Brown, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

In addition to hair follicles, atypical cells in mycosis fungoides may rarely be tropic to eccrine glands. In the even rarer syringotropic mycosis fungoides (syringolymphoid hyperplasia), these are the principal or only lesions observed. The eccrine duct and the eccrine gland are typically involved and eccrine epithelium may appear hyperchromatic and atypical, mimicking eccrine carcinoma. Lesions manifest as red to skin-colored papules, red to brown patches, or red scaly plaques. Hair loss without mucinous degeneration in the affected areas is common. Most reported cases have been in men; in one series, only 4 of 14 patients were female. [64]


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