What is the prognosis of nasal-type NK/T-cell lymphoma?

Updated: Apr 20, 2020
  • Author: Lauren C Pinter-Brown, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Nasal-type NK/T-cell lymphoma manifesting in the skin is highly aggressive, and patients have a median survival period of less than 12 months. [58, 59] The most important factor in predicting a poor outcome is the initial presence of extracutaneous involvement. Patients first seen with only cutaneous involvement had a median survival of 27 months, compared with months for patients presenting with cutaneous and extracutaneous disease. [59]

CD30+, CD56+ patients seem to have a better prognosis, possibly being examples of cutaneous anaplastic large cell lymphoma with coexpression of CD56. [60]

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