Which lab tests are indicated in the workup of mycosis fungoides cutaneous T-cell lymphoma (CTCL)?

Updated: Aug 15, 2018
  • Author: Lauren C Pinter-Brown, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

The following laboratory tests are included in the diagnostic workup of mycosis fungoides:

  • Complete blood count with differential; review the buffy coat smear for Sézary cells

  • Liver function tests: Look for liver-associated enzyme abnormalities

  • Uric acid and lactate dehydrogenase levels: These are markers of bulky and/or biologically aggressive disease

  • Flow cytometric study of the blood (include available T-cell–related antibodies): To detect a circulating malignant clone and to assess immunocompetence by quantifying the level of CD8-expressing lymphocytes

  • Human immunodeficiency virus (HIV) and human T-lymphotropic virus type 1 (HTLV-I) testing


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