What are the signs and symptoms of Sézary syndrome cutaneous T-cell lymphoma (CTCL)?

Updated: Apr 20, 2020
  • Author: Lauren C Pinter-Brown, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Sézary syndrome is defined by erythroderma and leukemia. Signs and symptoms include the following:

  • Edematous skin

  • Lymphadenopathy

  • Palmar and/or plantar hyperkeratosis

  • Alopecia

  • Nail dystrophy

  • Ectropion

  • Hepatosplenomegaly may be present

Ocular involvement may be evident in advanced CTCL. [3]

See Clinical Presentation for more detail.

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