Which antibiotics are used in the treatment of brucellosis?

Updated: Apr 22, 2021
  • Author: Nicholas John Bennett, MBBCh, PhD, FAAP, MA(Cantab); Chief Editor: Michael Stuart Bronze, MD  more...
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Although multiple antibiotics display in vitro activity against Brucella species, clinical response has been demonstrated with only a limited number of agents. Drugs that display clinical activity with low relapse rates include the following:

  • Doxycycline

  • Gentamicin

  • Streptomycin

  • Rifampin

  • Trimethoprim-sulfamethoxazole (TMP-SMZ)

Other agents with potential roles include the following:

  • Chloramphenicol

  • Imipenem-cilastatin

  • Tigecycline

  • Fluoroquinolones

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