What test is performed to diagnosis brucellosis relapse?

Updated: Apr 22, 2021
  • Author: Nicholas John Bennett, MBBCh, PhD, FAAP, MA(Cantab); Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Enzyme-linked immunosorbent assay (ELISA) typically uses the cytoplasmic proteins as antigens and measures IgM, IgG, and IgA, allowing better interpretation, especially in cases of brucellosis relapse. [44] This is because antibodies against LPS, which are used in agglutination tests, might persist for longer periods and are believed to yield higher sensitivity and specificity. ELISA of CSF also helps diagnose neurobrucellosis. Because levels should decrease with effective treatment, ELISA is also helpful in follow-up.


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