What is the role of cerebrospinal fluid analysis in the diagnosis of neurobrucellosis?

Updated: Apr 22, 2021
  • Author: Nicholas John Bennett, MBBCh, PhD, FAAP, MA(Cantab); Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

In patients with neurobrucellosis, analysis of CSF reveals a mild-to-modest lymphocytic pleocytosis of 88-98%. Protein levels are elevated in conjunction with normal glucose levels. CSF cultures are positive for brucellosis less than 50% of the time, but antibody testing of the fluid yields a diagnosis. CSF cultures are indicated for suggested meningitis.


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