What is the role of bone marrow culture in the diagnosis of brucellosis?

Updated: Apr 22, 2021
  • Author: Nicholas John Bennett, MBBCh, PhD, FAAP, MA(Cantab); Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Because the reticuloendothelial system holds a high concentration of brucellae, bone marrow culture is thought to be the criterion standard. Sensitivity is usually 80-90%. [43]

Any fluid (eg, synovial fluid, pleural fluid, or cerebrospinal fluid [CSF]) can be cultured, but the yield is usually low.


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