What neurologic findings suggest brucellosis?

Updated: Apr 22, 2021
  • Author: Nicholas John Bennett, MBBCh, PhD, FAAP, MA(Cantab); Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Neurologic findings vary according to the presentation of neurologic disease and may include the following:

  • Acute meningoencephalitis (most common neurologic manifestation) - Depressed level of consciousness, meningeal irritation, cranial nerve involvement, coma, seizure, and respiratory depression

  • Meningitis – Nuchal rigidity, Kerning sign, and Brudzinski sign

  • Increased intracranial pressure (ICP) or brain abscess – Papilledema, cranial nerve palsy, and focal neurologic deficits

  • Peripheral polyradiculoneuropathy - Hypotonia and areflexia in most cases, paraparesis, and an absence of sensory involvement

  • Diffuse CNS involvement - Spasticity, hyperreflexia, clonus, extensor plantar response, sensorineural hearing loss, cranial nerve involvement, and cerebellar signs


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