Which histologic findings are characteristic of bartonellosis (Bartonella infection)?

Updated: Jun 19, 2019
  • Author: Kassem A Hammoud, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Answer

Catscratch disease: Lymph node biopsy demonstrates granulomas with stellate necrosis, which are characteristic of catscratch disease. Silver stains, such as Dieterle or Warthin-Starry, may show bacilli.

Bacillary angiomatosis and peliosis hepatitis: Both of these disorders show blood vessel proliferation. Bacillary angiomatosis refers to vascular tumors that readily bleed when cut. The microscopic appearance of neovascular proliferation is diagnostic. Silver stains may demonstrate clusters of Bartonella bacilli. Peliosis refers to blood-filled cystic lesions that may be microscopic or up to a few millimeters in diameter. These lesions are characteristically found in the liver but are occasionally found in the spleen. Bacilli may be visible on electron microscopy.


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