Which medications in the drug class Corticosteroids are used in the treatment of Status Asthmaticus?

Updated: Jun 17, 2020
  • Author: Constantine K Saadeh, MD; Chief Editor: John J Oppenheimer, MD  more...
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Answer

Corticosteroids

These agents decrease the inflammatory response observed in asthma. They also decrease capillary leak and augment beta-receptor response to beta-adrenergic agents.

Prednisone

Prednisone decreases inflammation by suppressing the production of leukotrienes and the migration of polymorphonuclear leukocytes and by reducing capillary permeability.

Prednisolone (Pediapred, Millipred, Orapred)

Prednisolone decreases inflammation by suppressing the production of leukotrienes and the migration of polymorphonuclear leukocytes and by reducing capillary permeability.

Methylprednisolone (Solu-Medrol, Depo-Medrol, A-Methapred, Medrol)

Prednisone and methylprednisolone interfere with arachidonic acid metabolism and the production of leukotrienes, reduce microvascular leakage, reduce cytokine production, and prevent the migration of inflammatory cells.


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