Which drug interactions should be considered when using theophylline for the treatment of status asthmaticus?

Updated: Jun 17, 2020
  • Author: Constantine K Saadeh, MD; Chief Editor: John J Oppenheimer, MD  more...
  • Print
Answer

Theophylline also has significant drug interactions with medications such as ciprofloxacin, digoxin, and warfarin. These interactions may decrease the rate of theophylline clearance by interfering with P-450 site metabolism. On the other hand, phenytoin and cigarette smoking can increase the rate of metabolism of theophylline and, therefore, can decrease the therapeutic level of the drug.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!